Gestational trophoblastic neoplasia, a case report.
Neoplasia trofoblástica gestacional, a propósito de un caso
Article Sidebar
PDF (Español (España))
FLIP
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.
Main Article Content
Gestational Trophoblastic Neoplasia encompasses a broad spectrum of invasive placental diseases, including invasive mole, choriocarcinoma, placental site tumor, and epithelioid trophoblastic tumor. Clinical case: In this report, we analyze the clinical case of a 26-year-old postpartum patient who was diagnosed late with choriocarcinoma due to low clinical suspicion and an unusual presentation of the disease. The aim of this work is to raise awareness among readers about the importance of establishing a precise and timely diagnosis of GTN. Additionally, a thorough discussion of the topic will be conducted, providing insights for early disease diagnosis and classification to reduce associated complications.
Downloads
Article Details
Vree M, van Trommel N, Kenter G, Sweep F, ten Kate-Booij M, Massuger L, Lok C. The influence of lung metastases on the clinical course of gestational trophoblastic neoplasia: A historical cohort study. BJOG: An International Journal of Obstetrics & Gynaecology [Internet]. 2015;123(11):1839-1845. Disponible en: https://doi.org/10.1111/1471-0528.13622
Creasman J, Mannell W, McMeekin R, Mutch DG. Clinical gynecologic oncology. Elsevier [Internet]. 2018;143:79-85. Disponible en: https://www.scopus.com/record/display.uri?eid=2-s2.0-85042793053&origin=inward&txGid=30d7562d99d9e117f512a8c816ebbcfd
Devita V, Lawrence T, Rosenberg S. Cancer. Principles & Practice of Oncology (10th Edition). Wolters Kluwer Health. 1069 (2015).
Taylor S, Eisenstein K, Gildenstern V, Price H, Hingorani P, Patel A, Page N, Bailey S, Carpentieri D. Metastatic choriocarcinoma masquerading as a congenital glabellar hemangioma. Pediatric and Developmental Pathology [Internet]. 2018;22(1):59-64. Disponible en: https://doi.org/10.1177/1093526618765039
Ngan H, Seckl M., Berkowitz R, Xiang Y, Golfier F, Sekharan P K, Lurain J R, Massuger L. Update on the diagnosis and management of gestational trophoblastic disease. International Journal of Gynecology and Obstetrics [Internet]. 2018;143: 79-85. Disponible en: https://doi.org/10.1002/ijgo.12615
Mello JB, Ramos Cirilo PD, Michelin OC, Custódio Domingues MA, Cunha Rudge MV, Rogatto SR, Maestá I. Genomic profile in gestational and non-gestational choriocarcinomas. Placenta [Internet]. 2017;50:8-15. Disponible en: https://doi.org/10.1016/j.placenta.2016.12.009
Candelier J, Frappart L, Diatta A, Yadaden T, Cissé M, Afoutou J, Picard J, Mennesson B, Slim R, Si-Tayeb K, Coullin P. Differential expression of E-cadherin, β-catenin, and Lewis X between invasive hydatidiform moles and post-molar choriocarcinomas. Virchows Archiv [Internet]. 2013;462(6):653-663. Disponible en: https://doi.org/10.1007/s00428-013-1427-z
Hui P. Gestational trophoblastic tumors: A timely review of diagnostic pathology. Archives of Pathology; Laboratory Medicine [Internet]. 2018;143(1):65-74. Disponible en: https://doi.org/10.5858/arpa.2018-0234-ra
Clark J, Slater S, Seckl M. Treatment of gestational trophoblastic disease in the 2020s. Current Opinion in Obstetrics and Gynecology [Internet]. 2020;33(1):7-12. Disponible en: https://doi.org/10.1097/gco.0000000000000674
Lawrie TA, Alazzam M, Tidy J, Hancock BW, Osborne R. First-line chemotherapy in low-risk gestational trophoblastic neoplasia. Cochrane Database Syst Rev [Internet]. 2016;2019(6):CD007102. Disponible en: http://dx.doi.org/10.1002/14651858.CD007102.pub4
Horowitz NS, Eskander RN, Adelman MR, Burke W. Epidemiology, diagnosis, and treatment of gestational trophoblastic disease: A Society of Gynecologic Oncology evidenced-based review and recommendation. Gynecologic Oncology. 2021 Dec;163(3):605-13.
Al Riyami N, Department of Obstetrics and Gynecology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman, Al Riyami M, Al Hajri AT, Al Saidi S, Salman B, et al. Gestational trophoblastic disease at sultan Qaboos university hospital: Prevalence, risk factors, histological features, sonographic findings, and outcomes. Oman Med J [Internet]. 2019;34(3):200-4. Disponible en: http://dx.doi.org/10.5001/omj.2019.39
Chawla T, Bouchard-Fortier G, Turashvili G, Osborne R, Hack K, Glanc P. Gestational trophoblastic disease: an update. Abdom Radiol (NY) [Internet]. 2023;48(5):1793-815. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36763119/
Soper, J. Gestational trophoblastic disease: Current evaluation and management. Obstetrics and Gynecology [Internet]. 2021;137(2):355-370. Disponible en: https://doi.org/10.1097/aog.0000000000004240
Eysbouts Y, Bulten J, Ottevanger P, Thomas C, ten Kate-Booij, M van Herwaarden, A Massuger. Trends in incidence for gestational trophoblastic disease over the last 20years in a population-based study. Gynecologic Oncology [Internet] 2016;140(1):70–75. Disponible en: https://doi.org/doi:10.1016/j.ygyno.2015.11.01410.1016/j.ygyno.2015.11.014
Chawla T, Bouchard-Fortier G, Turashvili G, Osborne R, Hack K, Glanc P. Gestational trophoblastic disease: an update. Abdom Radiol (NY) [Internet]. 2023;48(5):1793-815. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36763119/
Mangili G, Lorusso D, Brown J, Pfisterer J, Massuger L, Vaughan M, et al. Trophoblastic Disease review for diagnosis and management: A joint report from the International Society for the study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup. Int J Gynecol Cancer [Internet]. 2014;24(Supp 3):S109–16. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25341573/
Seckl MJ, Sebire NJ, Fisher RA, Golfier F, Massuger L, Sessa C. Gestational trophoblastic disease: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol [Internet]. 2013;24:vi39–50. Disponible en: https://pubmed.ncbi.nlm.nih.gov/23999759/
