Gastric medullary carcinoma.
Carcinoma medular gástrico.
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Medullary carcinoma of the stomach (GMC) is a rare and poor differentiated neoplasm with better prognosis that shares many characteristic with medullary tumors of breast, lung, nasopharynx, thymus and salivary gland. Diagnosis includes positivity in PAS-alcian blue, alcian blue, Masson’s trichrome, and reticulin. Gastric medullary carcinoma shows an important lymphoid infiltration (T and B cells), dendritic, plasmodials and giant multinucleated macrophagues in close relations with neoplasic cells. Genomic results suggest that Epstein-Barr virus (EBV) becomes associated with GMC.
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