Characterization of pediatric patients with medulloblastoma in a referral center in Bogotá from 2011 to 2018
Caracterización de pacientes pediátricos con meduloblastoma tratados en un centro de referencia en Bogotá en el periodo 2011 a 2018
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Central nervous system (CNS) tumors are the most prevalent solid neoplasms in pediatrics. Medullo- blastoma is the most frequent embryonal tumor of the CNS and corresponds to approximately 20% of cases. Objective: to describe the experience in the diagnosis, treatment, and results of patients with medulloblastoma in a reference center in Colombia. Methods: 38 patients were included from January 2011 to December 2018. Results: those under 3 years of age received treatment based on the CCG9921 protocol and those over 3 years of age treatment based on the ACNS0332 protocol. Overall survival at 5 years was 50.6%. The overall survival of the entire group is low compared to countries with higher incomes due to multiple factors such as access barriers. Conclusion: It is im- portant to establish national guidelines that allow earlier diagnosis and risk-adjusted treatment. Also, it is important to collect information from multiple centers in order to evaluate the results and propose improvements in health policies.
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