Kikuchi- Fujimoto's disease: a great imitator. About a case.

La enfermedad de Kikuchi-Fujimoto: una gran imitadora. A propósito de un caso

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Antonio José Paredes Fernández
Miguel Ángel Mina Hinestroza
Melissa Fernanda Lara Viáfara
Valeria Andrea Gualtero García
Rodrigo Cárdenas-Perilla
Harol Cuello Bueno
Rigoberto Gómez Gutiérrez
Abstract

Kikuchi-Fujimoto disease (KFD) is a great mimic. Its clinical presentation resembles infectious entities, as well as reumatological diseases, lymphoproliferative disorders, or metastatic lesions. It is a benign, rare, self-limited entity of unknown etiology. It generally affects the cervical lymph nodes, and its symptoms are varied. The following is the case of a previously healthy 29-year-old man with generalized lymphadenopathy associated with significant unintended weight loss, intermittent high fever, nocturnal sweating, and general malaise. Fluorine-18-labeled deoxyglucose positron emission tomography (PET / CT 18F-FDG) revealed multiple nodes with intense metabolic activity suggestive of malignancy, infectious entities, or autoimmune diseases, which were ruled out. Histopathological diagnosis confirmed necrotizing histiocytic lymphadenitis, compatible with KFD, a rare and underdiagnosed disease, where early recognition could avoid unnecessary diagnostic or therapeutic interventions.

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Author Biographies (SEE)

Antonio José Paredes Fernández, Universidad Libre, Cali, Colombia.

Residente de Medicina interna. Departamento de Medicina Interna, Grupo Interinstitucional de Medicina Interna 1 (GIMI1), Universidad Libre, Cali (Colombia).

Miguel Ángel Mina Hinestroza , Clínica Imbanaco

Médico general, Universidad Icesi, Clínica Imbanaco, Cali (Colombia).

Melissa Fernanda Lara Viáfara , Universidad Libre, Cali, Colombia.

Residente de Medicina interna, Departamento de Medicina Interna, Grupo Interinstitucional de Medicina Interna 1 (GIMI1), Universidad Libre, Cali (Colombia).

Valeria Andrea Gualtero García, Universidad Libre, Cali, Colombia.

Estudiante Medicina general, Universidad Libre, Cali (Colombia).

Rodrigo Cárdenas-Perilla, Clínica Imbanaco

Médico nuclear, Departamento de Medicina Nuclear, Clínica Imbanaco, Cali (Colombia).

Harol Cuello Bueno, Clínica Imbanaco

Médico Patólogo. Departamento de Patología, Clínica Imbanaco, Cali (Colombia).

Rigoberto Gómez Gutiérrez, Clínica Imabanco. Universidad Libre, Cali, Colombia.

Especialista en Medicina interna, hematología y oncología. Hemato-oncólogos SA, Clínica Imbanaco, Cali. Departamento de Medicina Interna, Grupo Interinstitucional de Medicina Interna 1 (GIMI1), Universidad Libre, Cali (Colombia).

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