Progenitores de los tumores cerebrales.
Stem cells in brain tumors.
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El dogma sobre la génesis de las células es un evento insignificante en el cerebro de los mamíferos adultos, que ha influenciado nuestra percepción y la comprensión del origen y desarrollo de los tumores del sistema nervioso central. El descubrimiento de que las neuronas y la neuroglia se generan a lo largo de la vida a partir de células progenitoras proporciona nuevas posibilidades para definir la clonalidad y el comportamiento de las neoplasias cerebrales. La hipótesis detrás de este hallazgo está soportada por las modificaciones celulares y los mecanismos genéticos que controlan la neurogénesis normal y tumoral, lo que permite la identificación de nuevas estrategias terapéuticas.
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