Clinical and pathological characteristics of lung cáncer. Características clínicas y patológicas de cáncer de pulmón.

Abstract

Introduction and objective: Lung cancer is the leading cause of incidence and mortality in the world. The main purpose of this study is to describe the clinical and pathological characteristics of lung cancer patients, their overall survival and progression-free survival. Materials and methods: This is a descriptive, observational and retrospective study realized with lung cancer patients during the time period of 1 of January 2005 to 21 of March 2016. Descriptive analysis were preformed using central tendency, location and dispersion methods for continuous variables and absolute and relative frequencies for categorical variables and survival curves with the Kaplan-Meier method. Results: 224 patients were identified with an average age of 65 years old and 52% were males. Their clinical stage was IIB and IV in 83% of them, 58% had functional stage ECOG 0-1. 20% had cerebral metastasis, histologically 65% were adenocarcinomas and 12% were EGFR positive. The median overall survival was 18.9 months for advanced cases (IIIB y IV) and progression-free survival was 11.6 months. Conclusions: In this study the average age was 65 years old, the most common histology type was adenocarcinoma, and 12% had the mutation for the EGF receptor and survival was similar than the one found in medical literature.