The first report of institutional cancer registry in a center located in Medellín, Colombia Primer reporte del registro institucional de pacientes con cáncer, en un centro de Medellín, Colombia

Abstract

Purpose: This is the first report of an institutional-based cancer registry in Clínica de Oncología Astorga, in Medellín, Colombia. It was created to produce local information on socio-demographic and clinical characteristics, therapies, and survival outcomes of patients with the most frequent tumors in the institution.  Methods: All consecutive patients with cancers of the breast (BC), prostate (PC), lung (LC), colorectal (CRC), ovarian, stomach, pancreas, cervical, and melanoma, diagnosed after January 1/2019, and treated at the institution were included. A description of the entire cohort and of the five most frequent tumor types was performed. Kaplan-Meier curves for each tumor stage were used to estimate overall survival (OS) and progression-free survival (PFS). Statistical analysis was performed using SPSS v22. Results: Data from 729 patients were analyzed. The median follow-up was 12.0 months (IQR 5.8-18.1). The main diagnoses were BC, PC, CRC, LC, and cervical cancer in 57.2%, 10.2%, 8.0%, 7.7%, and 5.8% of patients, respectively. The most frequent stage at diagnosis was: stage II for BC (36.6%) and PC (35.1%), stage III for CRC (62.1%) and cervical cancer (50.0%), and stage IV for LC (62.5%).  In BC cases, the median PFS for stage IV patients was 10.8 months (95%CI: 8.7-13.0). In LC cases, median PFS and OS for stage IV were 5.6 months (95%CI: 4.1-7.0), and 6.8 months (95%CI: 2.5-11.1), respectively.  Conclusion: Even though follow-up is short in this first report, PFS for metastatic BC and PFS and OS for metastatic LC reflect the aggressive nature of these conditions in Colombia.