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Kikuchi- Fujimoto's disease: a great imitator. About a case.
La enfermedad de Kikuchi-Fujimoto: una gran imitadora. A propósito de un caso
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Paredes Fernández AJ, Mina Hinestroza M Ángel, Lara Viáfara MF, Gualtero García VA, Cárdenas-Perilla R, Cuello Bueno H, et al. Kikuchi- Fujimoto’s disease: a great imitator. About a case. Rev. colomb. hematol. oncol. [Internet]. 2022 Nov. 1 [cited 2025 Dec. 5];9(1):37-46. https://doi.org/10.51643/22562915.376
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Paredes Fernández AJ, Mina Hinestroza M Ángel, Lara Viáfara MF, Gualtero García VA, Cárdenas-Perilla R, Cuello Bueno H, et al. Kikuchi- Fujimoto’s disease: a great imitator. About a case. Rev. colomb. hematol. oncol. [Internet]. 2022 Nov. 1 [cited 2025 Dec. 5];9(1):37-46. https://doi.org/10.51643/22562915.376
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Kikuchi-Fujimoto disease (KFD) is a great mimic. Its clinical presentation resembles infectious entities, as well as reumatological diseases, lymphoproliferative disorders, or metastatic lesions. It is a benign, rare, self-limited entity of unknown etiology. It generally affects the cervical lymph nodes, and its symptoms are varied. The following is the case of a previously healthy 29-year-old man with generalized lymphadenopathy associated with significant unintended weight loss, intermittent high fever, nocturnal sweating, and general malaise. Fluorine-18-labeled deoxyglucose positron emission tomography (PET / CT 18F-FDG) revealed multiple nodes with intense metabolic activity suggestive of malignancy, infectious entities, or autoimmune diseases, which were ruled out. Histopathological diagnosis confirmed necrotizing histiocytic lymphadenitis, compatible with KFD, a rare and underdiagnosed disease, where early recognition could avoid unnecessary diagnostic or therapeutic interventions.
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- Mansoor CA, Shemin Z. Kikuchi-Fujimoto disease with multiple extra-nodal features - A clinical mimic. Reumatismo. [Internet] 2019;71(2):105-7. Disponible en https://doi.org/10.4081/reumatismo.2019.1130
- Perry AM, Choi SM. Kikuchi-Fujimoto Disease: A Review. Arch Pathol Lab Med. [Internet] 2018;142(11):1341-6. Disponible en https://doi.org/10.5858/arpa
- Halawa ARR, Ahmad MK, Nashwan AJ. An atypical presentation of Kikuchi-Fujimoto disease: A case report & literature review. Clin Case Reports. [Internet] 2020;8(12):3515-9. Disponible en https://doi.org/10.1002/ccr3.3373
- Qadri F, Atkin G, Thomas D, Das S. Kikuchi’s disease: an important cause of cervical lymphadenopathy. Clin Med (Northfield Il). [Internet] 2007;7(1):82-4. Disponible en: https://www.rcpjournals.org/lookup/doi/10.7861/clinmedicine.7-1-82
- López-Villegas VJ, Medina-Morales DA, Alzate-Piedrahita JA, Moreno Aguirre A, Saldarriaga Rivera LM. Kikuchi-Fujimoto disease in a patient with systemic lupus erythematosus and generalised lymphadenopathy. Case report. Rev Colomb Reumatol. [Internet] 2018;25(3):216-20. Disponible en https://doi.org/10.1016/j.rcreue.2019.01.002
- Moreno Moreno LP, Gutiérrez JM, Uribe AM. Linfadenitis necrotizante en lupus eritematoso sistémico y enfermedad de Kikuchi Fujimoto. Rev Colomb Reumatol. [Internet] 2011;18(2):135-9. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-81232011000200006&lng=en&nrm=iso
- Botero-Echeverri JC, Muriel-Hurtado CM, Arteta Cueto AA. Una relación potencialmente peligrosa: lupus eritematoso sistémico y enfermedad de Kikuchi – Fujimoto. CES Med. [Internet] 2016;225-30. Disponible en: https://revistas.ces.edu.co/index.php/medicina/article/view/3375
- Kikuchi M. Lymphadenitis showing focal reticulum cells hyperplasia with nuclear debris and phagocytosis: A clinicopathological study. (1972).
- Astudillo L. La maladie de Kikuchi-Fujimoto. La Rev Médecine Interne. [Internet] 2010;31(11):757-65. Disponible en: https://doi.org/10.1016/j.revmed.2010.01.011
- Jiwani RA, Jourdan DN, Pona A, Donthi D, Stalls JS, Rehana RW. Kikuchi Fujimoto disease: sinister presentation, good prognosis. J Community Hosp Intern Med Perspect. [Internet] 2021;11(1):72-75. Disponible en: https://doi.org/10.1080/20009666.2020.1824332
- Ha M, Je BK, Lee ES, Lee SW. Kikuchi disease manifesting as multifocal lymphadenopathy and splenomegaly: Ultrasonography, CT, and 18F-FDG PET/CT findings mimicking lymphoma. J Korean Soc Radiol. [Internet] 2020;81(1):1-6. Disponible en: http://doi.org/10.3348/jksr.2020.0009
- Kucukardali Y, Solmazgul E, Kunter E, Oncul O, Yildirim S, Kaplan M. Kikuchi-Fujimoto Disease: Analysis of 244 cases. Clin Rheumatol. [Internet] 2007;26(1):50-4. Disponible en: https://doi.org/10.1007/s10067-006-0230-5
- Meller J, Altenvoerde G, Munzel U, Jauho A, Behe M, Gratz S, et al. Fever of unknown origin: prospective comparison of [18F]FDG imaging with a double-head coincidence camera and gallium-67 citrate SPET. Eur J Nucl Med. [Internet] 2000;27nov(11):1617-25. Disponible en: https://doi.org/10.1007/s002590000341
- Li B, Zhang Y, Hou J, Cai L, Shi H. Synchronous Kikuchi-Fujimoto disease and gastric adenocarcinoma mimicking malignant lymphoma on 18 F-FDG PET/CT. Rev Esp Med Nucl Imagen Mol. [Internet] 2016;35(4):277-8. Disponible en: https://doi.org/10.1016/j.remn.2015.08.014
- Kong E, Chun K, Hong Y, Hah J, Cho I. 18F-FDG PET/CT findings in patients with Kikuchi disease. Nuklearmedizin. [Internet] 2013;52(3):101-6. Disponible en: https://doi.org/10.3413/Nukmed-0513-12-06
- Seong H, Jeong YH, Ji LW, Kim JH, Kim JH, Ahn JY, et al. Increased uptake of fluorine-18 fluoro-2-deoxy-D-glucose (F18-FDG) in the spleen: A novel marker for severe Kikuchi-Fujimoto disease. Res Sq. [Internet] 2021;preprint. Disponible en: https://doi.org/10.21203/rs.3.rs-32657/v1
- P Mghanga F, Bakari KH, Mayala HA. The Role of PET/CT in the Diagnosis of Kikuchi-Fujimoto Disease: A Case Series and Review of the Literature. J Mol Imaging Dyn. [Internet] 2017;7:2. Disponible en: https://doi.org/10.4172/2155-9937.1000139
- Tsujikawa T, Tsuchida T, Imamura Y, Kobayashi M, Asahi S, Shimizu K, et al. Kikuchi-Fujimoto Disease. Clin Nucl Med. [Internet] 2011;36(8):661-4. Disponible en: https://doi.org/10.1097/MD.0000000000000220
- Al Ghadeer HA, AlKadhem SM, AlMajed MS, AlAmer HM, AlHabeeb JA, Alomran SH, et al. Kikuchi-Fujimoto Disease Following COVID-19. Cureus [Internet] 2022;14(1): e21049. Disponible en: https://www.cureus.com/articles/79959-kikuchi-fujimoto-disease-following-covid-19
- Pepe F, Disma S, Teodoro C, Pepe P, Magro G. Kikuchi-Fujimoto disease: a clinicopathologic update. Pathologica. 2016;108(3):120-129. PMID: 28195263
- Song JY, Lee J, Park DW, Sohn JW, Suh S Il, Kim IS, et al. Clinical outcome and predictive factors of recurrence among patients with Kikuchi’s disease. Int J Infect Dis. [Internet] 2009;13(3):322-6. Disponible en: https://doi.org/10.1016/j.ijid.2008.06.022
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