Trombosis asociada a asparaginasa en niños con leucemia linfoblástica aguda.
Asparaginase-related thrombosis in children with acute lymphoblastic leukemia.
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La asparaginasa es un medicamento fundamental en el tratamiento contra la leucemia linfoblástica aguda. Su uso se asocia a disminución en la síntesis de proteínas que intervienen en el proceso de coagulación y fibrinolisis, lo que conlleva complicaciones trombóticas. La ocurrencia de estos eventos se ha informado después del inicio del tratamiento, reflejando así una posible interacción entre la enfermedad y la terapia.
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