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Trombosis asociada a asparaginasa en niños con leucemia linfoblástica aguda.

Asparaginase-related thrombosis in children with acute lymphoblastic leukemia.



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Trombosis asociada a asparaginasa en niños con leucemia linfoblástica aguda.
Rev. colomb. hematol. oncol. [Internet]. 2018 Jul. 1 [cited 2024 Dec. 22];5(1):72-8. Disponible en: https://doi.org/10.51643/22562915.365

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Carolina Casas
    Gloria Ramos
      Óscar Eduardo González
        Federico Arroyave

          Carolina Casas,

          Médica especialista en hematooncología pediátrica. Hospital Infantil Napoleón Franco Pareja (Cartagena).


          Gloria Ramos,

          Bacterióloga especialista en hemostasia. Hospital Militar Central. Laboratorio de Referencia en Hemostasia y Hematología H&H Lab (Bogotá).


          Óscar Eduardo González,

          Médico especialista en hematooncología pediátrica. Fundación Santa Fe. Hospital Central de la Policía Nacional (Bogotá).


          Federico Arroyave,

          Médico especialista en hematooncología pediátrica. Universidad Militar Nueva Granada (Bogotá).


          La asparaginasa es un medicamento fundamental en el tratamiento contra la leucemia linfoblástica aguda. Su uso se asocia a disminución en la síntesis de proteínas que intervienen en el proceso de coagulación y fibrinolisis, lo que conlleva complicaciones trombóticas. La ocurrencia de estos eventos se ha informado después del inicio del tratamiento, reflejando así una posible interacción entre la enfermedad y la terapia.


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