Asparaginase-related thrombosis in children with acute lymphoblastic leukemia.

Trombosis asociada a asparaginasa en niños con leucemia linfoblástica aguda.

Published 2018-07-01

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Vol. 5 No. 1 (2018): Julio
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Asparaginase-related thrombosis in children with acute lymphoblastic leukemia.
Rev. colomb. hematol. oncol. [Internet]. 2018 Jul. 1 [cited 2024 Dec. 22];5(1):72-8. Disponible en: https://doi.org/10.51643/22562915.365
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Carolina Casas
Hospital Infantil Napoleón Franco Pareja
    Gloria Ramos
    Hospital Militar Central
      Óscar Eduardo González
      Fundación Santa Fe de Bogotá
        Federico Arroyave
        Universidad Militar Nueva Granada
          Show authors biography

          Carolina Casas,

          Médica especialista en hematooncología pediátrica. Hospital Infantil Napoleón Franco Pareja (Cartagena).

          Gloria Ramos,

          Bacterióloga especialista en hemostasia. Hospital Militar Central. Laboratorio de Referencia en Hemostasia y Hematología H&H Lab (Bogotá).

          Óscar Eduardo González,

          Médico especialista en hematooncología pediátrica. Fundación Santa Fe. Hospital Central de la Policía Nacional (Bogotá).

          Federico Arroyave,

          Médico especialista en hematooncología pediátrica. Universidad Militar Nueva Granada (Bogotá).

          Asparaginase is a key drug in the treatment of acute lymphoblastic leukemia. However, is associated with a decrease in the synthesis of proteins involved in the coagulation and fibrinolysis process, which leads to thrombotic complications. The occurrence of these events has been reported after the initiation of treatment, reflecting a possible interaction between disease and therapy.

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