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Large extrapulmonary Ewing's Sarcoma a diagnostic challenge: case report
Sarcoma de Ewing extrapulmonar de gran tamaño, un reto diagnóstico. Reporte de caso
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Burbano Andrade GA, Rojas Torres JP, Rosero Ruiz MA. Large extrapulmonary Ewing’s Sarcoma a diagnostic challenge: case report. Rev. colomb. hematol. oncol. [Internet]. 2024 Jun. 30 [cited 2025 Dec. 6];11(1):40-9. https://doi.org/10.51643/22562915.692
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Burbano Andrade GA, Rojas Torres JP, Rosero Ruiz MA. Large extrapulmonary Ewing’s Sarcoma a diagnostic challenge: case report. Rev. colomb. hematol. oncol. [Internet]. 2024 Jun. 30 [cited 2025 Dec. 6];11(1):40-9. https://doi.org/10.51643/22562915.692
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Ewing's sarcoma is a type of primary bone tumor, typically found in long and flat bones. It is less frequently located in the thoracic wall. It is noteworthy that the occurrence of a significantly large tumor in the rib cage is uncommon. Additionally, it is important to highlight that the prognosis is inversely proportional to the size of the tumor. Clinical case: We present the case of an 11-year-old Afro-descendant patient with no pathological history, presenting with fever, pleuritic pain, and dyspnea. Imaging studies, including a biopsy, revealed a tumor in the right costal arch (13 x 11 cm). Biopsy confirms Ewing's sarcoma. Chemotherapy is initiated with significant improvement by week 6. Pediatric oncological surgery successfully resects the tumor (6x7 cm) in the seventh costal arch with no complications. The patient continues with antineoplastic management and shows clinical improvement by week 12. Conclussion: Emphasizing the importance of clinical-pathological correlation, immunohistochemical studies are crucial for a definitive diagnosis, considering the histological characteristics specific to this sarcoma. Few cases in the literature report initial tumor size and its reduction post-chemotherapeutic therapy, highlighting the favorable outcome observed in the patient by week 12 of chemotherapy.
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