Characterization of a series of cases of patients diagnosed with Osler Weber Rendu in a care center in Cali, Colombia.

Caracterización de una serie de casos de pacientes con diagnóstico de Osler Weber Rendu en un centro de atención en Cali, Colombia

Hereditary hemorrhagic telangiectasia or Osler-Weber-Rendu syndrome is a hereditary disease rarely caused by multisystem vascular dysplasia. It is characterized by visceral or mucocutaneous angiodysplasias in the cardiovascular system, skin, lungs, gastrointestinal tract, and brain. Initial detection is based on the Curaçao criteria. Treatment is based on support according to the ongoing manifestation. Methods: in order to characterize a case series of 13 patients diagnosed with Osler Weber Rendu in a reference medical center in the city of Cali, Colombia an active search was carried out patients diagnosed with Osler Weber Rendu between January 2010 and January 2023 in the electronic clinical history system of the Hematology clinic for and descriptive statistics were applied for the results analysis. Results: 13 patients with a diagnosis of Osler Weber Rendu were identified, most of them had involvement of the skin and gastrointestinal tract, the treatment was support and correction of iron deficiency anemia.  Conclusions: There are few national epidemiological data regarding this entity. A better characterization of the population in question can encourage systematic decision-making and the creation of protocols and local consensus for timely management. The findings in this case series are similar to those reported in the world population.