Mortality in patients with hematological neoplasms receiving chemotherapy in the intensive care unit: a scope review.

Mortalidad en pacientes con neoplasias hematológicas que reciben quimioterapia en la unidad de cuidados intensivos: una revisión de alcance

Published 2022-05-02

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Vol. 8 No. 2 (2021): Julio-Diciembre
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Mortality in patients with hematological neoplasms receiving chemotherapy in the intensive care unit: a scope review.
Rev. colomb. hematol. oncol. [Internet]. 2022 May 2 [cited 2024 Dec. 22];8(2):179-90. Disponible en: https://doi.org/10.51643/22562915.380
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Carlos Alexis Villalobos Caballero
Fundación Universitaria de Ciencias de la Salud - Hospital de San José de Bogotá
    https://orcid.org/0000-0002-6584-172X
    Daniel Lorenzo Espinosa Redondo
    Fundación Universitaria de Ciencias de la Salud - Hospital de San José de Bogotá
      http://orcid.org/0000-0001-7796-2046
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      Carlos Alexis Villalobos Caballero,

      Residente de segundo año de Hematología, Fundación Universitaria de Ciencias de la Salud – Hospital de San José de Bogotá.

      Daniel Lorenzo Espinosa Redondo,

      Hematólogo, Instructor Asistente, Servicio de Hematología Fundación Universitaria de Ciencias de la Salud - Hospital de San José de Bogotá.

      Admissions to the intensive care unit (ICU) of patients with hematological malignancies (NH) are usually common. The interventions are aimed at acute management (ventilatory support, vasopressor); another intervention is chemotherapy (CT). The literature related to mortality in patients with NH who receive CT in the ICU is poor. Objective: To summarize the information available on mortality in patients with HN receiving CT in the ICU. Methods: Studies published between 2011 and 2021 of patients with NH admitted to the ICU who received CT during their stay were analyzed. The databases PubMed, Scielo, LILACS, Cochrane Library, Science Direct and Google Scholar were explored. The review was carried out according to the Joanna Brigss Institute (JBI) methodology for scoping reviews, adhering to the PRISMA-ScR guidelines. Results: 10 articles were included. Mortality was between 25 and 76.5%. Lymphoma was, with 50%, the most prevalent HN. The indications for CT in the ICU were as a treatment for the underlying pathology or as life support. Conclusion: CT is a feasible option in patients with NH selected within the ICU, However, prospective studies are required to corroborate the findings.

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