Multicentric osteosarcoma. Case report and literature review

Osteosarcoma multicéntrico. Reporte de un caso y revisión de la literatura

Published 2022-05-02

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Vol. 8 No. 2 (2021): Julio-Diciembre
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Clinic cases
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Multicentric osteosarcoma. Case report and literature review.
Rev. colomb. hematol. oncol. [Internet]. 2022 May 2 [cited 2024 Dec. 22];8(2):141-7. Disponible en: https://doi.org/10.51643/22562915.127
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Angel Castro Dajer
Universidad de Cartagena. Clínica Blas de Lezo
    https://orcid.org/0000-0001-7278-4412
    Kevin Andrés Montes Durango
    Clínica Blas de Lezo
      Perfil Google Scholar
      https://orcid.org/0000-0001-5807-6065
      Victor Andrés Rodriguez Balseca
      Clínica Blas de Lezo
        https://orcid.org/0000-0002-2791-5257
        Paternina Palomo Soraya
        Clínica Blas de Lezo
          Show authors biography

          Angel Castro Dajer,

          Oncólogo Pediatra Universidad Nacional de Colombia

          Kevin Andrés Montes Durango,

          Médico general, Universidad de Cartagena

          Victor Andrés Rodriguez Balseca,

          Médico general, Universidad de Cartagena

          Paternina Palomo Soraya ,

          Oncóloga pediatra, Hospital Profesor A. Posada, Buenos Aires, Argentina

          Osteosarcoma is an uncommon malignant neoplasm that occurs mainly in the pediatric population. Frequently, its clinical presentation and diagnosis occurs incidentally, since it lacks specific symptoms. Multicentric osteosarcoma is a rarer presentation of the disease with an incidence of 1% to 2% of all osteosarcomas. A clinical case of a 13-year-old female patient is presented with a diagnosis of multicentric osteosarcoma (distal diaphysiometaphyseal region of the left femur and right femur), who receives treatment with neoadjuvant chemotherapy, radiotherapy and surgical resection of the primary tumor focus. Patient receives neoadjuvant chemotherapy, radiotherapy for pulmonary tumor foci and surgical resection of primary tumor focus with 100% tumor necrosis and reduction in number, size and activity on lung tumor. We concluded that the initial clinical suspicion of multiple foci is essential when diagnosing osteosarcoma as a strategy to improve the patient's approach, which can considerably improve survival with new diagnosis and treatment strategies, leading it to be considered a curable pathology.

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