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Response to vismodegib in recurrent meduloblastoma.

Respuesta a vismodegib en un meduloblastoma recurrente.



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Imágenes en hematología y oncología

Cómo citar
Response to vismodegib in recurrent meduloblastoma.
Rev. colomb. hematol. oncol. [Internet]. 2013 Oct. 1 [cited 2024 Dec. 22];2(3):45-51. Disponible en: https://doi.org/10.51643/22562915.353

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Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.

Laura Bernal
    Nicolás Useche
      Sonia Bermúdez
        Andrés Felipe Cardona

          Laura Bernal,

          Clinical and Translational Oncology Group, Institute of Oncology, Fundación Santa Fe de Bogotá (Bogotá, Colombia).


          Nicolás Useche,

          Diagnostic Image Department, Neuro-Radiology Section, Fundación Santa Fe de Bogotá (Bogotá, Colombia).


          Sonia Bermúdez,

          Diagnostic Image Department, Neuro-Radiology Section, Fundación Santa Fe de Bogotá (Bogotá, Colombia).


          Andrés Felipe Cardona,

          Clinical and Translational Oncology Group, Institute of Oncology, Fundación Santa Fe de Bogotá (Bogotá, Colombia). Foundation for Clinical and Applied Cancer Research (FICMAC); ONCOLGroup associate researcher.


          A 32 year-old female patient was seen in 2006 suffering from headaches, vertical diplopia and a gradually developing unsteady gait. CT scan revealed a 40 x 40 mm intra-axial cerebellar mass affecting the vermis. She underwent gross total resection with histology being compatible with a primitive neuro-ectodermal pattern. The final report was consistent with a desmoplastic nodular medulloblastoma (WHO grade IV), 20% Ki67, with focal reactivity for synaptophysin,  neurofilaments and CD99.

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